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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGAP5 All Species: 7.58
Human Site: S116 Identified Species: 18.52
UniProt: A6NIR3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIR3 NP_001137472 663 72983 S116 H V S T E R F S Q Q Y S S C S
Chimpanzee Pan troglodytes XP_001141446 439 48772
Rhesus Macaque Macaca mulatta XP_001082744 804 89081 A231 D V A Q K I V A T R K K Q Q L
Dog Lupus familis XP_848466 936 102470 S363 D Y S S S V P S T P S T S Q K
Cat Felis silvestris
Mouse Mus musculus Q8BXK8 857 94393 S284 D Y S S S V P S T P S T S Q K
Rat Rattus norvegicus Q8CGU4 1186 124419 S600 A S N G G H T S D Y S S S L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRL1 864 95088 S287 S S V P S T P S T S Q K E L R
Zebra Danio Brachydanio rerio Q08CI4 339 38765
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NGC3 995 108026 Y377 E N N N I T K Y N P G A A N S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C6C3 776 87784 T147 F V S L K K N T R G D I V A E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.6 57.2 49.6 N.A. 52.8 29.5 N.A. N.A. N.A. 48.1 22.4 N.A. 30.5 N.A. N.A. N.A.
Protein Similarity: 100 64.7 65.9 58.7 N.A. 61.4 38.5 N.A. N.A. N.A. 59.2 33.9 N.A. 42.9 N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 20 N.A. 20 20 N.A. N.A. N.A. 6.6 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 0 33.3 33.3 N.A. 33.3 26.6 N.A. N.A. N.A. 6.6 0 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 10 0 0 0 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 30 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % D
% Glu: 10 0 0 0 10 0 0 0 0 0 0 0 10 0 10 % E
% Phe: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 10 0 0 0 0 10 10 0 0 0 0 % G
% His: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 20 10 10 0 0 0 10 20 0 0 20 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 0 0 0 20 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 20 10 0 0 10 0 10 0 0 0 0 10 0 % N
% Pro: 0 0 0 10 0 0 30 0 0 30 0 0 0 0 10 % P
% Gln: 0 0 0 10 0 0 0 0 10 10 10 0 10 30 0 % Q
% Arg: 0 0 0 0 0 10 0 0 10 10 0 0 0 0 10 % R
% Ser: 10 20 40 20 30 0 0 50 0 10 30 20 40 0 20 % S
% Thr: 0 0 0 10 0 20 10 10 40 0 0 20 0 0 0 % T
% Val: 0 30 10 0 0 20 10 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 20 0 0 0 0 0 10 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _